TMZ reports that Odom was kicked out Wednesday by Kardashian, 29, when the NBA star refused an intervention.
According to the site, their marriage is on the rocks due his issues regarding substance abuse.
According to People, Kardashian has been battling to help her husband and save their marriage.
“It’s a really hard time for Khloé,” a source told People. “She’s kept this secret for almost two years trying to save Lamar and their marriage.”
In 2001, Kardashian’s husband was suspended by NBA when he admitted to smoking marijuana.
Meanwhile, Khloé Kardashian Odom took to Twitter to comment on the latest rumors.
She wrote: “Really hard to sit here and listen to people talk s— about my family! F— you and shame on you! I’m too protective for this s—!”
TMZ also spoke with Lamar’s rep saying he “is fine.”